Pharmacology Animation
Pharmacology Animation
  • Видео 124
  • Просмотров 3 812 177
DMARDs: Disease Modifying Anti-Rheumatoid Drugs
This video briefly illustrates the major concepts of DMARDs. The video starts with balancing the benefits and drawbacks of NSAIDs and corticosteroids in management of rheumatoid arthritis. Then it briefly compares between DMARDs and biologics. The main DMARDs are mentioned in the video.
Special attention was given to suggested mechanism of action of methotrexate and leflunomide drugs.
Просмотров: 3 398

Видео

Paracetamol: How does it work ?? The four suggested mechanism of actions
Просмотров 4,9 тыс.3 года назад
This video briefly discuss the four suggested mechanism of actions of Paracetamol, which include: 1- Serotonin pathway 2- Cyclooxygenase pathway 3- Cannabinoid pathway 4- opioid pathway
Biologics Drugs: Treatment of rheumatoid arthritis
Просмотров 11 тыс.3 года назад
Biologics are treatment derived from a biological process rather than being manufactured chemically. Biologics can be broadly classified into two major groups; Anti-Tumour necrosis factor alpha and others. Among various cytokines, Tumour necrosis factor alpha is the main target of for many biologics Therefore, will start with the anti-tumour necrosis factor. In the TNFα producing cells such as ...
Paracetamol (Acetaminophen): Mechanism of Action
Просмотров 24 тыс.3 года назад
This animated video briefly illustrate the four suggested pathways which might mediate the mechanisms of actions of Paracetamol (Acetaminophen) 1- Serotonin Pathway 2- Eicosanoids Pathways 3- Cannabinoids Pathways 4- Opioids Pathways Additionally it explains why there are two different name for the same drug : Paracetamol and Acetaminophen.
Paracetamol (Acetaminophen) hepatotoxicity and its management.
Просмотров 59 тыс.4 года назад
This animated video illustrates the mechanisms of Paracetamol (Acetaminophen) induce hepatotoxicity. It compares the production of toxic intermediate NAPQI under both therapeutic and toxic concentration of paracetamol. Glutathions plays important role in transforming NAPQI into water soluble no toxic metabolite that is readily excreted by the kidney This video also explain why paracetamol induc...
Pus, Neutrophils and Antigen Presenting Cells APCs
Просмотров 7 тыс.4 года назад
This short video briefly illustrates the role of neutrophils in inflammation and pus formation. Additionally, it illustrates the connection between neutrophils and other antigen presenting cells.
Leukotrienes in 2 minutes ; Production and Inhibitor drugs
Просмотров 29 тыс.4 года назад
This video briefly illustrate the production of leukotrienes. In addition to summary of their inflammatory roles. Then the drugs that inhibit leukotrienes production such as zileuton, zafirlukast and montelukast
Ant-inflammatory groups in 2 minutes: NSAIDs, Glucocorticoid, Zileuton, Zafirlukast and Montelukast
Просмотров 1,8 тыс.4 года назад
Eicosanoids are strongly involved in mediating inflammation; therefore, all eicosanoids inhibitors work as anti-inflammatory agents. Starting from the early step in the eicosanoid production pathway Corticosteroids, specifically the glucocorticoids, interfere with the phospholipase A2 enzyme Therefore, interfere with the production of almost all types of inflammatory eicosanoids. Indeed, glucoc...
Baroreceptors, Cardiovascular and CNS
Просмотров 4,4 тыс.4 года назад
Blood pressure regulation How our body compensate the sudden elevation of blood pressure Increased blood pressure will stretch the baroreceptors located in the aortic and carotid sinuses. The baroreceptors in turn will stimulate the cardioinhibitory centre in the medulla oblongata Which will enhance the parasympathetic activities through vagus nerve. This results in decreased heart rate or brad...
Antibodies : structures, functions and types
Просмотров 44 тыс.4 года назад
This short video briefly illustrates the general structure of the antibody. There are 5 types of antibodies; IgD, IgE, IgG, IgA and IgM. there are many functions for antibodies, among them; 1- Agglutination 1- Antibody mediated phagocytes 3- Antibody mediated cellular toxicities
Eicosanoids in 2 minutes; Prostaglandins, Prostacyclin, Thromboxane and Leukotrienes
Просмотров 33 тыс.4 года назад
This animated video illustrates in 2 minutes the production of important ecosanoids starting from catalysis of cell membrane phospholipids by phospholipase enzyme to produce arachidonic acid The cyclooxygenase enzyme pathways produce prostanoids, which include Prostaglandins, Prostacyclin, and Thromboxane The lipoxygenase enzyme pathways produce various leukotrienes
NSAIDs, corticosteroids , leukotrienes inhibitors. Anti-inflammatory groups
Просмотров 1,4 тыс.4 года назад
This video briefly illustrated the major ant-inflammatory drug groups, such as steroids, NSAIDs (selective and selective COX enzyme inhibitors) and leukotrienes inhibitors such as, zileuton , zafirlukast and montelukast
Cardinal signs of inflammation: Prostaglandins and Leukotrienes
Просмотров 17 тыс.4 года назад
There are five cardinal signs of inflammation. Swelling, Pain, Redness, Heat and loss of function Now we will see how eicosanoids especially prostaglandins and leukotrienes mediate these inflammatory signs. Prostaglandins are released from endothelial and inflammatory cells such as macrophages or dendritic cells They stimulate nerve endings producing a state of hyperalgesia Which makes nerves m...
Paracetamol or Acetaminophen: Why we have two different names across the Atlantic?
Просмотров 11 тыс.4 года назад
We have two different names Paracetamol and Acetaminophen for the same drug because American and British have chosen different letters from the same chemical formula which is (para-acetylamino phenol)
Baroreceptors, Sympathetic, Parasympathetic, Medulla oblongata and Renin- Angiotenisn
Просмотров 7 тыс.4 года назад
Blood pressure regulation How our body compensate the sudden elevation of blood pressure Increased blood pressure will stretch the baroreceptors located in the aortic and carotid sinuses. The baroreceptors in turn will stimulate the cardioinhibitory centre in the medulla oblongata Which will enhance the parasympathetic activities through vagus nerve. This results in decreased heart rate or brad...
Statins, cholesterol and atherosclerosis
Просмотров 7 тыс.4 года назад
Statins, cholesterol and atherosclerosis
Receptors and Second Messenger system; G-protein, Enzyme linked and Ligand gated ion channels
Просмотров 52 тыс.4 года назад
Receptors and Second Messenger system; G-protein, Enzyme linked and Ligand gated ion channels
Renin - Angiotenisn inhibitors: ACEi, ARB and Aliskerin.
Просмотров 7 тыс.4 года назад
Renin - Angiotenisn inhibitors: ACEi, ARB and Aliskerin.
Ant-inflammatory drugs. Steroids , NSAIDs and leukotrienes inhibitors
Просмотров 19 тыс.4 года назад
Ant-inflammatory drugs. Steroids , NSAIDs and leukotrienes inhibitors
Antiplatelet: Aspirin, Clopidogrel and Abciximab in 2 mins
Просмотров 29 тыс.4 года назад
Antiplatelet: Aspirin, Clopidogrel and Abciximab in 2 mins
T helper cells in 1 minute
Просмотров 39 тыс.4 года назад
T helper cells in 1 minute
Inflammation from PAMP to MHC
Просмотров 1,3 тыс.4 года назад
Inflammation from PAMP to MHC
Antibodies: Structures, types and functions
Просмотров 79 тыс.4 года назад
Antibodies: Structures, types and functions
PAMPs and TLRs : Pathogen Associated Molecular Patterns, and Toll Like Receptors.
Просмотров 27 тыс.4 года назад
PAMPs and TLRs : Pathogen Associated Molecular Patterns, and Toll Like Receptors.
Innate and adaptive immune system
Просмотров 2,4 тыс.4 года назад
Innate and adaptive immune system
How to draw cell structures using power point in 10 minutes. Lecturers and students
Просмотров 1,4 тыс.4 года назад
How to draw cell structures using power point in 10 minutes. Lecturers and students
مقدمة سريعة عن المضادات البكتيرية Antibacterial علم الادوية مع د جهاد حماد
Просмотров 2,5 тыс.5 лет назад
مقدمة سريعة عن المضادات البكتيرية Antibacterial علم الادوية مع د جهاد حماد
Funny sperm race in the cervix: contraceptive progesterone
Просмотров 1,5 тыс.5 лет назад
Funny sperm race in the cervix: contraceptive progesterone
علم الادوية مع دكتور جهاد حماد: المضادات البكتيرية Antibacterials
Просмотров 2,4 тыс.5 лет назад
علم الادوية مع دكتور جهاد حماد: المضادات البكتيرية Antibacterials
Neurofibrillary tangles and Tau protein (Alzheimer)
Просмотров 11 тыс.5 лет назад
Neurofibrillary tangles and Tau protein (Alzheimer)

Комментарии

  • @Paul-hu1ht
    @Paul-hu1ht 11 дней назад

    Sorry, but the voice/quality is like nails scraping down a blackboard 😨😨

  • @FarahAlshabot
    @FarahAlshabot 12 дней назад

    Thanks!

  • @thehonkening1
    @thehonkening1 13 дней назад

    So the"hermetic cells" are basically the bad guy?

  • @vijinakoovva3291
    @vijinakoovva3291 28 дней назад

    Thank you 🎉It helpful

  • @user-mu8yn7hr4k
    @user-mu8yn7hr4k 29 дней назад

    Thanks

  • @biscuitstix_
    @biscuitstix_ Месяц назад

    sound quality is a bit crunchy, but the video is simple and straightforward

  • @bio366geethasankar7
    @bio366geethasankar7 Месяц назад

    🥹🙏🙏🏻

  • @bio366geethasankar7
    @bio366geethasankar7 Месяц назад

    🙏🥹🙏🏻

  • @miamarvel616
    @miamarvel616 Месяц назад

    was this audio taken in a tunnel

  • @md.shamsulhudagalib2055
    @md.shamsulhudagalib2055 Месяц назад

    Ma shaa Allah

  • @qingyuansun3332
    @qingyuansun3332 Месяц назад

    very clear

  • @starry-eyed_68
    @starry-eyed_68 Месяц назад

    you are angels, thank you

  • @cumarcalicumar8299
    @cumarcalicumar8299 Месяц назад

    thanks i watch this video 5 times

  • @AubreyÆsohn
    @AubreyÆsohn 2 месяца назад

    Fascinating

  • @behumand9612
    @behumand9612 2 месяца назад

    wow! amazing stuff

  • @Cheeruppy6166
    @Cheeruppy6166 2 месяца назад

    Thank you very much helpful

  • @AnfalArshadCh
    @AnfalArshadCh 2 месяца назад

    Thank you

  • @minabish1783
    @minabish1783 2 месяца назад

    Thank you❤️

  • @madihashan2693
    @madihashan2693 2 месяца назад

    No animation

  • @thomashalm8585
    @thomashalm8585 2 месяца назад

    Wow so good for med students as I dont need to know the details of this

  • @Rene-uz3eb
    @Rene-uz3eb 2 месяца назад

    It is ridiculous how good I feel on albendazole, like body it getting the rest it needed for so long. I think it must be because it's a iron chelator and, unlike probably any other chelator, it can cross the bbb. Iron in the brain may be harder to dislodge out of all the organs exactly because other chelators can't get to the brain. Neurocyst would also react to withdrawal of iron esp since alb can enter the parasite cells, but I think the bigger effect is removing excess iron in the brain right now. And iron overload causes hypercalcemia. In the brain this can lead to psychiatric symptoms on its own. EDIT: there is an optimal dose. Too much, and it chelates all the currently mobilized iron, preventing necessary processes. Result is you feel exhausted. Ideal seems to be twice a day to keep even level, and enough to remove a good fraction of the (newly) mobilized iron. Going by how good I feel, holy grail stuff. EDIT: never mind, take as much iron out as you can. It stopped working well not after I increased the dose, but after some idiot supplement company started adding iron to my B12 patches without telling anyone they did, was only in the small print. 3 weeks later I finally notice it. Unfortunately no brand names exist in B12 patches, dropping that stuff. Goes to show you really want to avoid iron intake from any source, whether on iron chelators or not. EDIT: iron chelators kick up antioxidant use. I do take vitamin C regularly, but apparently my batch went bad (clumped up). You do not want to be severely vitamin C deficient (apart from other antioxidants the body will fall back on), believe me (no energy, shortness of breath, injuries don't heal). The more chelation the more C is needed. EDIT: iron chelation is 'unnatural' and makes excessive use on vitamins, which leads to depletion on normal food intake. Unfortunately every vitamin is essential, so take a multi vitamin. I don't know which ones it depleted, but probably B vitamins cause I didn't supplement those. Moral of the story: if you are on any drug, you MUST take a multivitamin (without iron of course. And extra magnesium, to provide coactivation for the extra amount of thiamine, and calcium phosphate, because many drugs are calcium wasting).

  • @aliali-fd7lx
    @aliali-fd7lx 3 месяца назад

    Thank you so much

  • @ellios5734
    @ellios5734 3 месяца назад

    What I needed

  • @HassanAliNursing
    @HassanAliNursing 3 месяца назад

    Amazing thank you

  • @rusulabdalkreem9098
    @rusulabdalkreem9098 3 месяца назад

    ليش ماكو صوت بالفديو ؟ 😢

  • @rusulabdalkreem9098
    @rusulabdalkreem9098 3 месяца назад

    عاشت ايدك دكتورة على هذا الشرح العظيم

  • @cyrus3035
    @cyrus3035 3 месяца назад

    thank you... genuinely helpful

  • @Flow_State1991
    @Flow_State1991 3 месяца назад

    Hello, What to do when Terbinafine hasn't worked for Jock Itch after an 8 week course?

  • @Daydreamer-qg7zv
    @Daydreamer-qg7zv 3 месяца назад

    You simply explained it in just 3 minutes hats off to you❤

  • @mmproduccionmusical1350
    @mmproduccionmusical1350 3 месяца назад

    could you write the source/journal article where you found this information?

  • @behnambahreini
    @behnambahreini 3 месяца назад

    Nice ❤

  • @nonalife0470
    @nonalife0470 3 месяца назад

    Great,thank you doctor.

  • @behnambahreini
    @behnambahreini 3 месяца назад

    Very nice❤

  • @kashifofficial5820
    @kashifofficial5820 3 месяца назад

    Absolutely stunning Allah bless you

  • @fariataxnim
    @fariataxnim 4 месяца назад

    Thank you!

  • @ridhijain2446
    @ridhijain2446 4 месяца назад

    Kindly provide reference for the same

  • @rn_noor_222
    @rn_noor_222 4 месяца назад

    Thank you so much I got it 👍🏻

  • @arry9396
    @arry9396 4 месяца назад

    Thank you so much❤

  • @TheTomahawkRepublic
    @TheTomahawkRepublic 4 месяца назад

    Yet again Trump was right

  • @matthewfoulger4682
    @matthewfoulger4682 4 месяца назад

    Complete bullshit and sponsored by big pharma

  • @AI-dl6kb
    @AI-dl6kb 4 месяца назад

    Really helped me to have an overview to this pathway, thanks a lot!

  • @Sabrinasound
    @Sabrinasound 4 месяца назад

    Thanks for the info! I’ve always wondered why!😊

  • @LawdyLawdy
    @LawdyLawdy 4 месяца назад

    Thanks Dr. Hammad. Was having trouble understandings this drug family.

  • @loganmarshall7380
    @loganmarshall7380 4 месяца назад

    Amazing❤

  • @user-mm6ny1oj6t
    @user-mm6ny1oj6t 4 месяца назад

    Bahar ❤👍

  • @Aliyu_Umar
    @Aliyu_Umar 4 месяца назад

    Simple, straightforward, and concise.

  • @easolis24
    @easolis24 4 месяца назад

    What type of Dr can identify which type I am?

  • @jonathanpicket124
    @jonathanpicket124 4 месяца назад

    Those are not mechanisms, they are phenotypes.

  • @aisyasofea5974
    @aisyasofea5974 4 месяца назад

    Thank you

  • @nightmarevstplugin3944
    @nightmarevstplugin3944 5 месяцев назад